Kinetics of cytokines and chemokines gene expression distinguishes Paracoccidioides brasiliensis infection from disease.

@article{Mamoni2005KineticsOC,
  title={Kinetics of cytokines and chemokines gene expression distinguishes Paracoccidioides brasiliensis infection from disease.},
  author={Ronei Luciano Mamoni and Maria Heloisa Souza Lima Blotta},
  journal={Cytokine},
  year={2005},
  volume={32 1},
  pages={20-9}
}
The human infection with Paracoccidioides brasiliensis may result in three major outcomes: the paracoccidioidomycosis-infection (PI), the adult form (AF) and the juvenile form (JF) of the disease. The aim of this study was to compare the immunological response among these groups. The gene expression of multiple cytokines, including IL-4, IL-5, IL-6, IL-10, IFN-gamma, TNF-alpha and TGF-beta1, and chemokines, CXCL8, CXCL9 and CXCL10 was evaluated by RT-PCR in peripheral blood mononuclear cells… CONTINUE READING

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