Kinetics of corneal epithelial maintenance and graft loss. A population balance model.

  title={Kinetics of corneal epithelial maintenance and graft loss. A population balance model.},
  author={Ashu Sharma and William H. Coles},
  journal={Investigative ophthalmology & visual science},
  volume={30 9},
We use a population balance model to study the mechanism and the rate of centripetal migration of epithelial cells, renewal of the corneal epithelial population by the cell derived from (progeny of) the limbal stem cells and the kinetics of the replacement of the donor corneal epithelium. The epithelial mass is constant under the normal circumstances and therefore the rate of cellular entry due to centripetal motion and mitosis into any epithelial volume must equal the cell loss from the same… CONTINUE READING
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