Kinetics of and rate equations for the uptake of alpha-amino-isobutyric aicd and gamma-aminobutyric acid by mouse brain slices incubated in a glucose-free medium containing pyruvate as the energy source.
Mouse cerebrum slices were incubated in a medium containing pyruvate instead of glucose as the energy source. After a preincubation period alpha-aminoisobutyric acid (AIB) or gamma-aminobutyric acid (GABA) was added, and the rate of uptake by the slices was measured. AIB and GABA are taken up to above their concentration in the medium. Although influx is… (More)