Kinetics of actin monomer exchange at the slow growing ends of actin filaments and their relation to the elongation of filaments shortened by gelsolin

@article{Janmey1986KineticsOA,
  title={Kinetics of actin monomer exchange at the slow growing ends of actin filaments and their relation to the elongation of filaments shortened by gelsolin},
  author={Paul A. Janmey and Thomas Peter Stossel},
  journal={Journal of Muscle Research & Cell Motility},
  year={1986},
  volume={7},
  pages={446-454}
}
The kinetics of actin monomer exchange with the slow growing pointed ends of actin filaments have been determined by measuring rates of monomer addition to or loss from filaments with their fast-growing barbed ends blocked by the protein gelsolin. Direct measurements of filament length by electron microscopy confirmed that each gelsolin acts as a nucleus for an actin filament. The rate constants ascertained arek −=0.03s−1;k +=0.06 μm −1 s−1 at 23° C andk −=0.11 s−1;k +=0.09 μm −1s−1 at 37° C… CONTINUE READING

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S t r u c t u r e a n d mobility of actin filaments as measured by quasielastic light

  • P. A. JANMEY, J. PEETERMANS, ZANER, T.P.K.S. STOSSEL, T. TANAKA
  • 1986

S t r u c t u r e a n d mobility of actin filaments as measured by quasielastic light scattering , viscometry , and electron microscopy

  • P. A. JANMEY, J. PEETERMANS, K. S. STOSSEL ZANER, P. T., T. TANAKA
  • J . biol . Chem .
  • 1986

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