Kinetics of Spanish broom peroxidase obeys a Ping-Pong Bi-Bi mechanism with competitive inhibition by substrates.

@article{Galende2015KineticsOS,
  title={Kinetics of Spanish broom peroxidase obeys a Ping-Pong Bi-Bi mechanism with competitive inhibition by substrates.},
  author={Patricia P{\'e}rez Galende and Nazaret Hidalgo Cuadrado and Eduard Ya Kostetsky and Manuel G. Roig and Enrique Villar and Valery L. Shnyrov and John Fitzgerald Kennedy},
  journal={International journal of biological macromolecules},
  year={2015},
  volume={81},
  pages={1005-11}
}
In plants, adverse conditions often induce an increase in reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). H2O2 is reduced to water, and thus becomes detoxified by enzymes such as Cytisus multiflorus peroxidase (CMP). Here, the steady-state kinetics of the H2O2-supported oxidation of different organic substrates by CMP was investigated… CONTINUE READING