Kinetics of In-111-platelets in the baboon: II. In vitro distribution and sites of sequestration.

@article{Kotz1985KineticsOI,
  title={Kinetics of In-111-platelets in the baboon: II. In vitro distribution and sites of sequestration.},
  author={Harry F Kotz{\'e} and Mattheus G. L{\"o}tter and P. N. Badenhorst and Anthon du P. Heyns},
  journal={Thrombosis and haemostasis},
  year={1985},
  volume={53 3},
  pages={408-10}
}
The kinetics and sites of sequestration of a fully representative population of In-111-platelets were determined in 11 baboons. The in vivo method of quantification with computer assisted scintillation camera image analysis was validated by sacrificing 5 baboons and measuring and comparing the distribution of organ radioactivity. Recovery of platelets in the circulation was 87% +/- 7, and their mean survival time was 147 hr +/- 15. The mean splenic platelet pool was 16.0 +/- 1.9. At equilibrium… CONTINUE READING