Kinetics of IgM and IgA Antibody Response to 23-Valent Pneumococcal Polysaccharide Vaccination in Healthy Subjects

@article{Schtz2012KineticsOI,
  title={Kinetics of IgM and IgA Antibody Response to 23-Valent Pneumococcal Polysaccharide Vaccination in Healthy Subjects},
  author={Katharina Sch{\"u}tz and Richard Geir Hughes and Antony J. Parker and Isabella Quinti and Vojtech Thon and Monica Cavaliere and Martina W{\"u}rfel and Wilhelm Herzog and Johannes Engelbert Gessner and Ulrich Baumann},
  journal={Journal of Clinical Immunology},
  year={2012},
  volume={33},
  pages={288-296}
}
PurposeA poor antibody response of IgM and IgA antibodies upon vaccination with pneumococcal polysaccharides (PnPS) is discussed as independent risk factors for bronchiectasis in patients with antibody deficiency syndrome (ADS) receiving immunoglobulin replacement therapy. However, the kinetics of the specific IgM and IgA response to vaccination with multivalent pneumococcal polysaccharides requires a more detailed knowledge. In this study we aimed i) to develop a standardised multivalent PnPS… CONTINUE READING

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