Kinetics of Fatty Acid Oxidation in Low Density Lipoproteins Evaluated by Registration of the Oxidizer Consumption and Reaction Product Yield

@article{Titov2005KineticsOF,
  title={Kinetics of Fatty Acid Oxidation in Low Density Lipoproteins Evaluated by Registration of the Oxidizer Consumption and Reaction Product Yield},
  author={Vladimir Nicolaevich Titov and Galina G. Konovalova and D. M. Lisitsyn and S. D. Razumovskiĭ and I. B. Nezhdanova and Valery V. Kukharchuk},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2005},
  volume={140},
  pages={38-40}
}
Oxidation of arachidonic acid by ROS in vitro can be evaluated by the formation of reaction products (conjugated dienes); this is preceded by a lag period caused by the action of antioxidants (α-tocopherol, β-carotene, and ascorbic acid). In case of ozone titration the oxidizer is consumed even during the lag period, when conjugated dienes are not yet forming. Comparison of the oxidation rate constants for antioxidants, arachidonic and oleic monoenic fatty acids suggests that during the lag… 
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