Kinetics of Clonazepam in Relation to Electroencephalographic and Clinical Effects

@article{Sthl1983KineticsOC,
  title={Kinetics of Clonazepam in Relation to Electroencephalographic and Clinical Effects},
  author={Y. St{\aa}hl and {\AA}. Persson and I. Petters and A. Rane and K. Theorell and P. Walson},
  journal={Epilepsia},
  year={1983},
  volume={24}
}
Summary: The aim of this study was to see if the immediate EEG and clinical response to an intravenous dose of clonazepam was predictive for the effect of oral clonazepam maintenance therapy. Four children with petit mal epilepsy were given clonazepam intravenously during continuous EEG recording. Clonazepam plasma concentrations were determined repeatedly with a high performance liquid chromatographic method using a reversed phase system. The day after the intravenous dose the patients were… Expand
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