Kinetics of Cl-dependent K fluxes in hyposmotically swollen low K sheep erythrocytes

@article{Delpire1991KineticsOC,
  title={Kinetics of Cl-dependent K fluxes in hyposmotically swollen low K sheep erythrocytes},
  author={Eric Delpire and Peter K. Lauf},
  journal={The Journal of General Physiology},
  year={1991},
  volume={97},
  pages={173 - 193}
}
A detailed kinetic study of K:Cl cotransport in hyposmotically swollen low K sheep red blood cells was carried out to characterize the nature of the outwardly poised carrier. The kinetic parameters were determined from the rate of K efflux and influx under zero-K-trans conditions in red cells with cellular K altered by the nystatin method and with different extracellular K or Rb concentrations. Although apparent affinities for efflux and influx were quite similar, the maximal velocity for K… CONTINUE READING