Kinetics of 2,4,6-trichlorophenol in different organs of the rat

  title={Kinetics of 2,4,6-trichlorophenol in different organs of the rat},
  author={Kaija Pekari and C. Boud{\`e}ne and Antero Aitio},
  journal={Archives of Toxicology},
The concentration of 2,4,6-trichlorophenol was measured in the blood and various other tissues of the rat after IP administration of the compound at 25 mg per kg body weight. The highest concentration, 329±117 nmol·g−1, was found in the kidney. Half-times were between 1.4 and 1.8 h in the blood, brain, fat, kidney, liver and muscle. The extent of conjugation of 2,4,6-trichlorophenol was also investigated by measuring total and free chlorophenol in the blood. 

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