Kinetics of [3H]trifluoperazine in bile fistula rats.

@article{Schmalzing1978KineticsO,
  title={Kinetics of [3H]trifluoperazine in bile fistula rats.},
  author={G. Schmalzing and U. Breyer},
  journal={Xenobiotica; the fate of foreign compounds in biological systems},
  year={1978},
  volume={8 1},
  pages={
          45-54
        }
}
  • G. Schmalzing, U. Breyer
  • Published 1978
  • Chemistry, Medicine
  • Xenobiotica; the fate of foreign compounds in biological systems
1. Anaesthetized male rats with a bile fistula received 12-3 micron mol/kg [9-3H]tri-fluoperazine into the tail vein, and the biliary excretion of total radioactivity, unchanged drug and phenolic glucuronides was followed for 8 h. 2. About half of the administered radioactivity apeared in bile within 8 h;80% of the biliary metabolites were unextractable even after beta-glucuronidasearylsulphatase hydrolysis; about 10% were glucuronides of 7-hydroxytrifluoperazine and its N-demethylated analogue… Expand
5 Citations
Radioimmunoassay for trifluoperazine in human plasma.
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Contribution of trifluoperazine metabolites to the in vivo 19F NMR spectrum of rat brain
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Metabolism and Kinetics

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