Kinetics and mechanism for the binding of HCN to cytochrome c oxidase.

Abstract

The kinetics of cyanide binding to cytochrome c oxidase were systematically studied as a function of [HCN], [oxidase], pH, ionic strength, temperature, type and concentration of solubilizing detergent, and monomer-dimer content of oxidase. On the basis of these results a minimum reaction mechanism is proposed in which the spectrally visible rapid and slow… (More)

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Cite this paper

@article{Panda1995KineticsAM, title={Kinetics and mechanism for the binding of HCN to cytochrome c oxidase.}, author={Markandeswar Panda and Neal C Robinson}, journal={Biochemistry}, year={1995}, volume={34 31}, pages={10009-18} }