Kinetics, Pharmacokinetics, and Regulation of l‐Carnitine and Acetyl‐l‐carnitine Metabolism

@article{Rebouche2004KineticsPA,
  title={Kinetics, Pharmacokinetics, and Regulation of l‐Carnitine and Acetyl‐l‐carnitine Metabolism},
  author={Charles J. Rebouche},
  journal={Annals of the New York Academy of Sciences},
  year={2004},
  volume={1033}
}
  • C. Rebouche
  • Published 1 November 2004
  • Biology, Medicine
  • Annals of the New York Academy of Sciences
Abstract: In mammals, the carnitine pool consists of nonesterified l‐carnitine and many acylcarnitine esters. Of these esters, acetyl‐l‐carnitine is quantitatively and functionally the most significant. Carnitine homeostasis is maintained by absorption from diet, a modest rate of synthesis, and efficient renal reabsorption. Dietary l‐carnitine is absorbed by active and passive transfer across enterocyte membranes. Bioavailability of dietary l‐carnitine is 54‐87% and is dependent on the amount… 
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TLDR
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TLDR
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TLDR
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