Kinetic properties of light-dependent ascorbic acid oxidation by melanin.

@article{Glickman1993KineticPO,
  title={Kinetic properties of light-dependent ascorbic acid oxidation by melanin.},
  author={R. Glickman and R. Sowell and K. Lam},
  journal={Free radical biology & medicine},
  year={1993},
  volume={15 4},
  pages={
          453-7
        }
}
  • R. Glickman, R. Sowell, K. Lam
  • Published 1993
  • Chemistry, Medicine
  • Free radical biology & medicine
  • The kinetic properties of ascorbic acid oxidation by light-activated melanin granules demonstrate the presence of a specific reactive site on the melanin granule saturable by ascorbic acid. Increased light intensity increased the Vmax and reduced the Km of this reaction, indicating increased affinity of the active site for ascorbic acid. The kinetics of this reaction are not markedly changed in a reduced-oxygen environment. Ascorbic acid oxidation is competitively inhibited by isoascorbic acid… CONTINUE READING
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