Kinetic profiling of in vivo lung cellular inflammatory responses to mechanical ventilation

@inproceedings{Woods2015KineticPO,
  title={Kinetic profiling of in vivo lung cellular inflammatory responses to mechanical ventilation},
  author={Samantha J. Woods and Alicia Achiaa Charlotte Waite and Kieran O'Dea and Paul Halford and Masao Takata and Michael Wilson},
  booktitle={American journal of physiology. Lung cellular and molecular physiology},
  year={2015}
}
Mechanical ventilation, through overdistension of the lung, induces substantial inflammation that is thought to increase mortality among critically ill patients. The mechanotransduction processes involved in converting lung distension into inflammation during this ventilator-induced lung injury (VILI) remain unclear, although many cell types have been shown to be involved in its pathogenesis. This study aimed to identify the profile of in vivo lung cellular activation that occurs during the… CONTINUE READING

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