Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment.

@article{Smith2004KineticPO,
  title={Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment.},
  author={J. Lleweilun Smith and Wendy J. Freebern and Irene Collins and Adriana De Siervi and Idalia Montano and Cynthia M. Haggerty and Markey C. McNutt and Wayne G Butscher and Inna Dzekunova and D. W. Petersen and Ernest Kawasaki and Juanita L Merchant and Kevin Gardner},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 32},
  pages={11554-9}
}
Understanding the language encrypted in the gene regulatory regions of the human genome is a challenging goal for the genomic era. Although customary extrapolations from steady-state mRNA levels have been effective, deciphering these regulatory codes will require additional empirical data sets that more closely reflect the dynamic progression of molecular… CONTINUE READING