Kinetic predictive techniques applied to lignocaine therapeutic drug monitoring.

Abstract

As lignocaine clearance is influenced by factors such as cardiac failure and liver impairment, clinical pharmacokinetic principles should be used to account for kinetic variability so that target concentrations are achieved consistently throughout the course of intravenous therapy. Two groups of patients with ischaemic heart disease, who received lignocaine… (More)

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@article{Joel1983KineticPT, title={Kinetic predictive techniques applied to lignocaine therapeutic drug monitoring.}, author={Smita Joel and Steve Bryson and M. Small and W. Stewart Hillis and Arthur Kelman and Bruce R. Whiting}, journal={Therapeutic drug monitoring}, year={1983}, volume={5 3}, pages={271-7} }