Kinetic hydrogen isotope effects in the ionization of some ketonic substances

  title={Kinetic hydrogen isotope effects in the ionization of some ketonic substances},
  author={Ronald Percy Bell and John E. Crooks},
  journal={Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences},
  pages={285 - 299}
  • R. Bell, J. E. Crooks
  • Published 20 July 1965
  • Chemistry
  • Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences
The kinetic hydrogen isotope effect has been measured for the water-catalysed bromination of acetylacetone, monobromoacetylacetone, ethyl acetoacetate, ethyl α-bromoacetoacetate, ethyl α-methylacetoacetate, ethyl malonate, ethyl monobromomalonate, and methyl methyl - malonate and for the bromination of ethyl a-methylacetoacetate catalysed by six basic anions. All these reactions are of zero order with respect to bromine, so that the process studied is the rate of transfer of a proton or… 
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