Kinetic exclusion assay technology: characterization of molecular interactions.

@article{Darling2004KineticEA,
  title={Kinetic exclusion assay technology: characterization of molecular interactions.},
  author={Ryan J Darling and P. Brault},
  journal={Assay and drug development technologies},
  year={2004},
  volume={2 6},
  pages={647-57}
}
Characterization of intermolecular interactions in terms of affinity, binding kinetics, stoichiometry, specificity, and thermodynamics can facilitate the selection of lead compounds in the discovery and development of protein therapeutics. KinExA (Sapidyne Instruments, Inc., Boise, ID) is a relatively new technology that is gaining use in characterizing molecular interactions, particularly with respect to antibody therapeutics. KinExA offers a platform that allows the measurement of true… CONTINUE READING

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