Kinetic determination of focal adhesion protein formation.


I examined the binding kinetics between integrin (alpha(IIb)beta(3)) and purified focal adhesion proteins, including alpha-actinin, filamin, vinculin, talin, and F-actin. Using static light-scatter technique, I observed affinities of the order talin > filamin > F-actin > alpha-actinin > (talin when bound to vinculin) which were lower when integrin was… (More)


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@article{Goldmann2000KineticDO, title={Kinetic determination of focal adhesion protein formation.}, author={Wolfgang Heinrich Goldmann}, journal={Biochemical and biophysical research communications}, year={2000}, volume={271 2}, pages={553-7} }