Kinetic basis for global loss of fidelity arising from mismatches in the P-site codon:anticodon helix.

Abstract

Faithful decoding of the genetic information by the ribosome relies on kinetically driven mechanisms that promote selection of cognate substrates during elongation. Recently, we have shown that in addition to these kinetically driven mechanisms, the ribosome possesses a post peptidyl transfer quality control system that retrospectively monitors the codon… (More)
DOI: 10.1261/rna.2241810

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Cite this paper

@article{Zaher2010KineticBF, title={Kinetic basis for global loss of fidelity arising from mismatches in the P-site codon:anticodon helix.}, author={Hani S. Zaher and Rachel Kramer Green}, journal={RNA}, year={2010}, volume={16 10}, pages={1980-9} }