Kinetic and thermodynamic aspects of the regioselective addition of bifunctional hydroxylaminooxime-type HO-nucleophiles to Pt-complexed nitriles.

@article{Luzyanin2006KineticAT,
  title={Kinetic and thermodynamic aspects of the regioselective addition of bifunctional hydroxylaminooxime-type HO-nucleophiles to Pt-complexed nitriles.},
  author={Konstantin V Luzyanin and Vadim Yu Kukushkin and Maxim L Kuznetsov and Alexander D Ryabov and Markus Galanski and Matti Haukka and Eugene V Tretyakov and Victor I Ovcharenko and Maximilian N Kopylovich and Armando J L Pombeiro},
  journal={Inorganic chemistry},
  year={2006},
  volume={45 5},
  pages={2296-306}
}
The coupling between coordinated propiononitriles in trans-[PtCln(EtCN)2] (n = 2, 4) and the 1,2-hydroxylaminooximes HON(H)CMe2C(R)=NOH (R = Ph 1, Me 2) proceeds smoothly in CHCl(3) at ca. 40-45 degrees C and gives trans-[PtCln{NH=C(Et)ON(H)CMe2C(R)=NOH}2] (n = 2, R = Ph 5, Me 6; n = 4, R = Ph 7, Me 8) in 80-85% isolated yields. The reaction is highly regioselective, and both spectroscopic (IR; FAB+-MS; 1D 1H, 13C{1H}, and 195Pt NMR; and 2D 1H,13C HMQC, 1H,13C HMBC, and 1H,15N HMQC NMR) and X… CONTINUE READING