Kinetic and HPV infection effects on cross-type neutralizing antibody and avidity responses induced by Cervarix(®).

@article{Kemp2012KineticAH,
  title={Kinetic and HPV infection effects on cross-type neutralizing antibody and avidity responses induced by Cervarix(®).},
  author={Troy J. Kemp and Mahboobeh Safaeian and Allan Hildesheim and Yuanji Pan and Kerri J. Penrose and Carolina Porras and John T. Schiller and Douglas R Lowy and Rolando Herrero and Ligia A. Pinto},
  journal={Vaccine},
  year={2012},
  volume={31 1},
  pages={165-70}
}
BACKGROUND We previously demonstrated that Cervarix(®) elicits antibody responses against vaccine-related types for which clinical efficacy was demonstrated (HPV-31 and -45). Here, we evaluated the kinetics of neutralization titers and avidity of Cervarix(®)-induced antibodies up to 36 months of follow-up in unexposed and HPV infected women. METHODS A subset of women who participated in the Cost Rica HPV-16/18 Vaccine Trial had pre- and post-vaccination sera tested for antibody responses to… CONTINUE READING

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