Kinetic analysis of DNA double-strand break repair pathways in Arabidopsis.

@article{Charbonnel2011KineticAO,
  title={Kinetic analysis of DNA double-strand break repair pathways in Arabidopsis.},
  author={Cyril Charbonnel and Elisabeth Allain and Maria Eugenia Gallego and Charles I White},
  journal={DNA repair},
  year={2011},
  volume={10 6},
  pages={611-9}
}
Double-strand breaks in genomic DNA (DSB) are potentially lethal lesions which separate parts of chromosome arms from their centromeres. Repair of DSB by recombination can generate mutations and further chromosomal rearrangements, making the regulation of recombination and the choice of recombination pathways of the highest importance. Although knowledge of recombination mechanisms has considerably advanced, the complex interrelationships and regulation of pathways are far from being fully… CONTINUE READING