Kinesin superfamily motor proteins and intracellular transport

  title={Kinesin superfamily motor proteins and intracellular transport},
  author={Nobutaka Hirokawa and Yasuko Noda and Yosuke Tanaka and Shinsuke Niwa},
  journal={Nature Reviews Molecular Cell Biology},
Intracellular transport is fundamental for cellular function, survival and morphogenesis. Kinesin superfamily proteins (also known as KIFs) are important molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs. The mechanisms by which different kinesins recognize and bind to specific cargos, as well as how kinesins unload cargo and determine the direction of transport, have now been identified. Furthermore, recent molecular… 

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Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head

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