Kinesin family 17 (osmotic avoidance abnormal-3) is dispensable for photoreceptor morphology and function.

@article{Jiang2015KinesinF1,
  title={Kinesin family 17 (osmotic avoidance abnormal-3) is dispensable for photoreceptor morphology and function.},
  author={Li Jiang and Beatrice M. Tam and Guoxing Ying and Sen Wu and William W. Hauswirth and Jeanne M. Frederick and Orson L Moritz and Wolfgang Baehr},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2015},
  volume={29 12},
  pages={
          4866-80
        }
}
In Caenorhabditis elegans, homodimeric [kinesin family (KIF) 17, osmotic avoidance abnormal-3 (OSM-3)] and heterotrimeric (KIF3) kinesin-2 motors are required to establish sensory cilia by intraflagellar transport (IFT) where KIF3 and KIF17 cooperate to build the axoneme core and KIF17 builds the distal segments. However, the function of KIF17 in vertebrates is unresolved. We expressed full-length and motorless KIF17 constructs in mouse rod photoreceptors using adeno-associated virus in Xenopus… CONTINUE READING

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