Kinesin I ATPase manipulates biohybrids formed from tubulin and carbon nanotubes.

Abstract

This chapter describes a method for the formation of novel protein-nanotube hybrid conjugates. Specifically, we took advantage of the self-assembly and self-recognition properties of tubulin cytoskeletal protein immobilized onto carbon nanotubes to form nanotube-based biohybrids. Further biohybrid hierarchical integration in assemblies enabled molecular-level manipulation on engineered surfaces, as demonstrated with biocatalyst kinesin 1 ATPase molecular motor. The method presented herein can be extended for the preparation of biocatalyst-based or protein-based assemblies to be used as sensors or biological templates for nanofabrication.

DOI: 10.1007/978-1-61779-132-1_7

Cite this paper

@article{Dinu2011KinesinIA, title={Kinesin I ATPase manipulates biohybrids formed from tubulin and carbon nanotubes.}, author={Cerasela Zoica Dinu and Shyam Sundhar Bale and Jonathan S. Dordick}, journal={Methods in molecular biology}, year={2011}, volume={743}, pages={77-93} }