Kinesin-2 is a motor for late endosomes and lysosomes.

  title={Kinesin-2 is a motor for late endosomes and lysosomes.},
  author={Christa L Brown and Kerstin C. Maier and Tobias Stauber and Laura M Ginkel and Linda Wordeman and Isabelle Vernos and Trina A Schroer},
  volume={6 12},
The bidirectional nature of late endosome/lysosome movement suggests involvement of at least two distinct motors, one minus-end directed and one plus-end directed. Previous work has identified dynein as the minus-end-directed motor for late endosome/lysosome localization and dynamics. Conventional kinesin (kinesin-1) has been implicated in plus-end-directed late endosome/lysosome movement, but other kinesin family members may also be involved. Kinesin-2 is known to drive the movement of pigment… CONTINUE READING