Kinesin's neck-linker determines its ability to navigate obstacles on the microtubule surface.

@article{Hoeprich2014KinesinsND,
  title={Kinesin's neck-linker determines its ability to navigate obstacles on the microtubule surface.},
  author={Gregory J. Hoeprich and Andrew Richard Christopher Thompson and Derrick P. McVicker and William O. Hancock and Christopher L. Berger},
  journal={Biophysical journal},
  year={2014},
  volume={106 8},
  pages={1691-700}
}
The neck-linker is a structurally conserved region among most members of the kinesin superfamily of molecular motor proteins that is critical for kinesin's processive transport of intracellular cargo along the microtubule surface. Variation in the neck-linker length has been shown to directly modulate processivity in different kinesin families; for example, kinesin-1, with a shorter neck-linker, is more processive than kinesin-2. Although small differences in processivity are likely obscured in… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
24 Citations
11 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 11 references

Similar Papers

Loading similar papers…