Kinase signaling pathways as potential targets in the treatment of Parkinson's disease.

@article{Greggio2007KinaseSP,
  title={Kinase signaling pathways as potential targets in the treatment of Parkinson's disease.},
  author={Elisa Greggio and Andrew A Singleton},
  journal={Expert review of proteomics},
  year={2007},
  volume={4 6},
  pages={
          783-92
        }
}
Parkinson's disease (PD) is a severe, progressive, age-associated, neurodegenerative disorder. Current therapies are symptomatic and not effective at halting or significantly slowing the disease progress. The search for etiologic-based therapies has focused largely on genetic findings made in familial forms of this disease. Mutations of five genes have been unequivocally linked to PD; two of these, LRRK2 and PINK1, encode kinases and as such are attractive tools with which to understand the… CONTINUE READING

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