Kinase dysfunction and kinase inhibitors.


With recent advances in molecular biology, abnormalities in cancer cells that contribute to dysregulation of cell survival and proliferation are being characterized with greater precision. Through this process, key abnormalities in cancer cells involving proteins that regulate signal transduction, migration, mitosis and other critical processes have been… (More)
DOI: 10.1111/j.1365-3164.2012.01081.x