Kinase dysfunction and kinase inhibitors.

  title={Kinase dysfunction and kinase inhibitors.},
  author={Cheryl A London},
  journal={Veterinary dermatology},
  volume={24 1},
With recent advances in molecular biology, abnormalities in cancer cells that contribute to dysregulation of cell survival and proliferation are being characterized with greater precision. Through this process, key abnormalities in cancer cells involving proteins that regulate signal transduction, migration, mitosis and other critical processes have been identified. Such abnormalities often involve a class of proteins called kinases that act to phosphorylate other proteins in the cell… CONTINUE READING