Killing by Bactericidal Antibiotics Does Not Depend on Reactive Oxygen Species

@article{Keren2013KillingBB,
  title={Killing by Bactericidal Antibiotics Does Not Depend on Reactive Oxygen Species},
  author={Iris Keren and Yanxia Wu and Julio Inocencio and Lawrence R. Mulcahy and Kim Lewis},
  journal={Science},
  year={2013},
  volume={339},
  pages={1213 - 1216}
}
Antibiotic Mechanisms Revisited Several recent studies have suggested that bactericidal antibiotics kill cells by a common mechanism involving reactive oxygen species (ROS). Two groups tested this hypothesis using diverse experiments, with both finding that quinolone, lactam, and aminoglycoside antibiotics had similar efficacy for killing in the presence or absence of oxygen (or nitrate). Liu et al. (p. 1210) saw no increase in hydrogen peroxide production in antibiotic-exposed cells and found… 

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