Killing activity of micafungin against Aspergillus fumigatus hyphae assessed by specific fluorescent staining for cell viability.

@article{Watabe2003KillingAO,
  title={Killing activity of micafungin against Aspergillus fumigatus hyphae assessed by specific fluorescent staining for cell viability.},
  author={Etsuko Watabe and Toru Nakai and Satoru Matsumoto and Fumiaki Ikeda and Kazuo Hatano},
  journal={Antimicrobial agents and chemotherapy},
  year={2003},
  volume={47 6},
  pages={
          1995-8
        }
}
We studied the anti-Aspergillus activity of micafungin by using two fluorescent dyes to detect cell viability. Micafungin induced flattened hyphae, caused by the bursting of cells, which had lost their viability. Micafungin has killing activity against actively growing hyphae, even though it is not fungicidal against the whole burden of Aspergillus fumigatus. 

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