Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

@article{Zhang2010KillerCI,
  title={Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.},
  author={Yan Zhang and Bo Wang and Shihui Ye and Sheng Liu and Mengli Liu and Chunmei Shen and Yan Teng and Jun Qi},
  journal={Leukemia research},
  year={2010},
  volume={34 1},
  pages={55-8}
}
Accumulating evidences suggest that killer cell immunoglobulin-like receptors (KIRs) contribute to the pathogenesis of diverse kinds of diseases. However, the functions and effects of KIR gene polymorphisms in the development of diseases remain largely unknown, especially about the activating KIR genes. To investigate the association of KIR gene polymorphisms with subtypes of leukemia, we carried out the present study on 263 patients with leukemia and 239 healthy controls by means of polymerase… CONTINUE READING
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