Kidney volume and functional outcomes in autosomal dominant polycystic kidney disease.

@article{Chapman2012KidneyVA,
  title={Kidney volume and functional outcomes in autosomal dominant polycystic kidney disease.},
  author={Arlene B. Chapman and James E. Bost and Vicente E. Torres and L. M. Guay-Woodford and Kyongtae T. Bae and Douglas Landsittel and Jie Li and Bernard F. King and Diego Mart{\'i}n and L. H. Wetzel and Mark E. Lockhart and Peter C. Harris and Marva M. Moxey-Mims and Mike Flessner and W. M. Bennett and J. J. Grantham},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2012},
  volume={7 3},
  pages={479-86}
}
BACKGROUND AND OBJECTIVES Autosomal dominant polycystic kidney disease (ADPKD) is characterized by increased total kidney volume (TKV) and renal failure. This study aimed to determine if height-adjusted TKV (htTKV) predicts the onset of renal insufficiency. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This prospective, observational, longitudinal, multicenter study included 241 adults with ADPKD and preserved renal function. Magnetic resonance imaging and iothalamate clearance were used to… CONTINUE READING
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