A physiological approach to recurrent nephrolithiasis and its genetic determinants
- Medicine, Biology
Timely diagnosis of genetic determinants of nephrolithiasis is warranted to prevent development of kidney injury; however, diagnosis is often delayed owing to unfamiliarity with these rare disorders.
Nephrolithiasis Management and Prevention: Current Perspectives
Improved awareness and education in both the general population and among health care providers about modifiable risk factors has the potential to improve general health and decrease morbidity and mortality secondary to kidney stone disease.
Nephrolithiasis; Prevalence, Risk factors and Therapeutic Strategies: A Review
- Medicine, BiologyMadridge Journal of Internal and Emergency Medicine
Data collected from In vivo, In vitro, and clinical trials suggest that medicinal plants could be used as an alternative therapeutic strategy in the management of nephrolithiasis.
Pathophysiology of nephrolithiasis
- Medicine, Biology
A PubMed based literature review on the recent advances in the pathophysiological mechanisms of kidney stone formation found that there is a link between diabetes, metabolic syndrome, obesity, insulin resistance and nephrolithiasis.
Review on Uro-Lithiasis Pathophysiology and Aesculapian Discussion
Managing diet, medication use, and food consumption can help prevent the organisation of kidney stones, and over the past 10 years major progress has been made in the pathogenesis of renal stone.
Understanding epidemiology and etiologic factors of urolithiasis: an overview
Better understanding of the various aspects of this disease including causative agents may provide an insight of this disorder to the researcher and common people in order to contain this disease.
Non-surgical management therapies for kidney stones.
An update on the non-surgical treatments of stone disease is provided, focusing on what is known and what is new in kidney stone management.
Kidney stones: Mechanism of formation, pathogenesis and possible treatments
The present work discusses the mechanism of stone formation, several forms of kidney stones as well as the various therapeutic measures for treatment of urinary stones including many medicinal plants as herbal option aswell as oxalate degrading enzyme.
New insights into the pathogenesis of renal calculi.
- MedicineThe Urologic clinics of North America
SHOWING 1-10 OF 145 REFERENCES
Cystinuria in childhood and adolescence: recommendations for diagnosis, treatment, and follow-up
- MedicinePediatric Nephrology
The underlying pathogenetic mechanisms are discussed, guidance for the diagnosis, therapy, and management of cystinuria is provided, and regular follow-up and optimal pharmacotherapy significantly increase stone-free intervals are provided.
The primary stone event: a new hypothesis involving a vascular etiology.
- Medicine, BiologyThe Journal of urology
The review of the literature and the study of the cholesterol content of renal stones support a new theory regarding the initial stone forming event of nephrolithiasis, based on multiple epidemiological, physiological, anatomical and clinical observations.
Citrate and renal calculi: new insights and future directions.
- Medicine, ChemistryAmerican journal of kidney diseases : the official journal of the National Kidney Foundation
Genetics of hypercalciuria and calcium nephrolithiasis: from the rare monogenic to the common polygenic forms.
- Medicine, BiologyAmerican journal of kidney diseases : the official journal of the National Kidney Foundation
What is known about monogenic renal calcium stone-related disorders is discussed, an update on genetic research in calcium nephrolithiasis and such intermediate phenotypes as idiopathic hypercalciuria is provided, and some method tools potentially useful in this research frame of reference are proposed.
[Urolithiasis in childhood].
- MedicineMonatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde
Promotory and inhibitory factors of stone formation are presented and their significance is explained by means of selected cases of selected patients, especially the relevance of modern strategies as e.g. the extracorporal shock wave lithotripsy, percutaneous litholapaxy and ureterorenoscopy are discussed.
Citrate and renal calculi: an update.
- MedicineMineral and electrolyte metabolism
Inhibition of stone recurrence has now been validated by a randomized trial and two promising products, calcium citrate as an optimum calcium supplement and potassium-magnesium citrate which may be superior to potassium citrate in the management of stone disease are identified.
Metabolic risk factors and the impact of medical therapy on the management of nephrolithiasis in obese patients.
- MedicineThe Journal of urology
Obesity, as a result of dietary indiscretion, probable purine gluttony and possible type II diabetes, appears to have a significant role in recurrent stone formation.
Pathophysiology of hypocitraturic nephrolithiasis.
- MedicineEndocrinology and metabolism clinics of North America
Pathophysiology of uric acid nephrolithiasis.
- Medicine, BiologyEndocrinology and metabolism clinics of North America
Molecular Etiology of Primary Hyperoxaluria Type 1: New Directions for Treatment
- BiologyAmerican Journal of Nephrology
The determination of the crystal structure of AGT has enabled the effects of some of the most important missense mutations in the AGXT gene to be rationalised in terms ofAGT folding, dimerization and stability, which has opened up new possibilities for the design pharmacological agents that might counteract the destabilizing effects of these mutations.