Kidney development in cadherin-6 mutants: delayed mesenchyme-to-epithelial conversion and loss of nephrons.

Abstract

During nephrogenesis, dynamic changes in the expression of cell adhesion molecules are evident as epithelial structures differentiate from the induced mesenchyme. The cadherins are thought to play an important role in the metanephric mesenchyme, when cells aggregate to form the renal vesicle, a polarized epithelial structure which eventually fuses with the… (More)

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@article{Mah2000KidneyDI, title={Kidney development in cadherin-6 mutants: delayed mesenchyme-to-epithelial conversion and loss of nephrons.}, author={Steven P Mah and Harald Saueressig and Margie Rauch Goulding and Chris Kintner and Greg Dressler}, journal={Developmental biology}, year={2000}, volume={223 1}, pages={38-53} }