Kidney development: regulatory molecules crucial to both mice and men.

  title={Kidney development: regulatory molecules crucial to both mice and men.},
  author={Carlton M. Bates},
  journal={Molecular genetics and metabolism},
  volume={71 1-2},
Although the study of embryonic kidney development began in the 1950s, three decades passed until scientists began identifying the molecular controls of renal organogenesis. Most of these advances have come from mouse gene targeting and rodent kidney explant manipulation. Translation of the rodent data to human congenital kidney disease has only just begun. The activities of those regulatory molecules proven to be used in common appear remarkably similar in mouse and human renal development… CONTINUE READING

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