Kidney-derived proteins in urine as biomarkers of induced acute kidney injury in sheep.

Abstract

Acute kidney injury (AKI) is a life-threatening condition for which an early diagnosis is problematic. The aim of the present study was to identify kidney-derived urinary proteins specific to AKI in sheep. AKI was induced in six sheep by an overdose of ketoprofen. Six untreated sheep served as controls. Urine samples were collected for up to 24 h after drug… (More)
DOI: 10.1016/j.tvjl.2011.10.004

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