Kidney derived micro-scaffolds enable HK-2 cells to develop more in-vivo like properties.

@article{Finesilver2014KidneyDM,
  title={Kidney derived micro-scaffolds enable HK-2 cells to develop more in-vivo like properties.},
  author={Gershon Finesilver and Jaques Bailly and Meygal Kahana and Eduardo Mitrani},
  journal={Experimental cell research},
  year={2014},
  volume={322 1},
  pages={71-80}
}
Many cell lines, despite the fact that they are easy to culture, tend to lose some of their in vivo characteristics in vitro, we therefore decided to investigate whether culturing HK-2 cells on kidney derived micro-scaffolds (KMS) could improve proximal tubule functionality to these cells. Kidney derived micro-scaffolds (KMS) have been prepared that, due to the fact that they are only 300 µm in depth, allow for transfer of gases and nutrients via diffusion whilst maintaining the kidney's… CONTINUE READING

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