Kidney and pancreas transplantation in type 1 diabetes mellitus.

@article{Lerner2008KidneyAP,
  title={Kidney and pancreas transplantation in type 1 diabetes mellitus.},
  author={Susan M Lerner},
  journal={The Mount Sinai journal of medicine, New York},
  year={2008},
  volume={75 4},
  pages={372-84}
}
Type 1 diabetes mellitus is characterized by autoimmune destruction of pancreatic beta cells, leading to a state of absolute insulin deficiency. Glycemic control via the use of exogenous insulin injections is often imperfect, resulting in multiple long-term complications, such as retinopathy, neuropathy, vasculopathy, and nephropathy. The Diabetes Control and Complications Trial has provided conclusive evidence that better glycemic control by intensive insulin treatment effectively delays the… CONTINUE READING

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