Kidney Organoids: A Translational Journey.

@article{Morizane2017KidneyOA,
  title={Kidney Organoids: A Translational Journey.},
  author={Ryuji Morizane and Joseph V. Bonventre},
  journal={Trends in molecular medicine},
  year={2017},
  volume={23 3},
  pages={
          246-263
        }
}
Human pluripotent stem cells (hPSCs) are attractive sources for regenerative medicine and disease modeling in vitro. Directed hPSC differentiation approaches have derived from knowledge of cell development in vivo rather than from stochastic cell differentiation. Moreover, there has been great success in the generation of 3D organ-buds termed 'organoids' from hPSCs; these consist of a variety of cell types in vitro that mimic organs in vivo. The organoid bears great potential in the study of… CONTINUE READING
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