Kidney Fibrosis: Origins and Interventions.

  title={Kidney Fibrosis: Origins and Interventions.},
  author={Thomas Vanhove and Roel Goldschmeding and Dirk Kuypers},
  volume={101 4},
All causes of renal allograft injury, when severe and/or sustained, can result in chronic histological damage of which interstitial fibrosis and tubular atrophy are dominant features. Unless a specific disease process can be identified, what drives interstitial fibrosis and tubular atrophy progression in individual patients is often unclear. In general, clinicopathological factors known to predict and drive allograft fibrosis include graft quality, inflammation (whether "nonspecific" or related… CONTINUE READING


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