Kidney–brain crosstalk in the acute and chronic setting

@article{Lu2015KidneybrainCI,
  title={Kidney–brain crosstalk in the acute and chronic setting},
  author={Renhua Lu and Matthew C Kiernan and Anne Murray and Mitchell H. Rosner and Claudio Ronco},
  journal={Nature Reviews Nephrology},
  year={2015},
  volume={11},
  pages={707-719}
}
Patients with kidney disease often exhibit multiple organ dysfunction that is caused, in part, by marked connectivity between the kidney and other organs and tissues. Substantial crosstalk occurs between the kidney and the brain, as indicated by the frequent presentation of neurological disorders, such as cerebrovascular disease, cognitive impairment, and neuropathy during the natural history of chronic kidney disease. The underlying pathophysiology of such comorbid neurological disorders in… CONTINUE READING
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