Kidins220/ARMS interacts with Pdzrn3, a protein containing multiple binding domains.

  title={Kidins220/ARMS interacts with Pdzrn3, a protein containing multiple binding domains.},
  author={Massimiliano Andreazzoli and Gaia Gestri and Elena Landi and Beatrice D'Orsi and Manuela Barilari and Angela Iervolino and Marianna Vitiello and Stephen W. Wilson and Luciana Dente},
  volume={94 9},
We report the identification of a novel partner of Kidins220/ARMS (Kinase D-interacting substrate of 220 kDa/Ankyrin Repeat-rich Membrane Spanning) an adaptor of neurotrophin receptors playing crucial roles during neurogenesis. Screening a phage display library of brain cDNA products we found that D. rerio Pdzrn3, a protein containing RING-finger and PDZ-domains, interacts with Kidins220/ARMS through its first PDZ-domain. Both zebrafish proteins share high homology with the corresponding… CONTINUE READING
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