KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.

@article{Gaytn2009KiSS1IT,
  title={KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.},
  author={Francisco X. Gayt{\'a}n and Mar{\'i}a Elena N{\'u}{\~n}ez Gayt{\'a}n and J. P. Castellano and M. Isabel Monge Romero and Juan Medina Roa and B. Argil{\'e}s Aparicio and Nuria Padilla Garrido and Jos{\'e} Eugenio S{\'a}nchez-Criado and Robert Peter Millar and Angel Antonio Blasco Pellicer and Hamish M. Fraser and M Tena-Sempere},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2009},
  volume={296 3},
  pages={
          E520-31
        }
}
Kisspeptins, the products of the KiSS-1 gene acting via G protein-coupled receptor 54 (GPR54), have recently emerged as pivotal signals in the hypothalamic network triggering the preovulatory surge of gonadotropins and, hence, ovulation. Additional actions of kisspeptins at other levels of the hypothalamic-pituitary-ovarian axis have been suggested but remain to date scarcely studied. We report herein the pattern of expression of KiSS-1 and GPR54 in the human and nonhuman primate ovary and… CONTINUE READING

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