Ki-ras mutation modifies the protective effect of dietary monounsaturated fat and calcium on sporadic colorectal cancer.

@article{Bautista1997KirasMM,
  title={Ki-ras mutation modifies the protective effect of dietary monounsaturated fat and calcium on sporadic colorectal cancer.},
  author={Diana Bautista and Ant{\`o}nia Obrador and Victor Moreno and Elena Cabeza and Ram{\'o}n Canet and Enric Benito and Xavier Bosch and Jla Costa},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={1997},
  volume={6 1},
  pages={
          57-61
        }
}
The geographic differences in the incidence of colorectal cancer have been mostly attributed to variations in diet. The diversity of the Mediterranean diet and the heterogeneity of acquired genetic alterations in colorectal cancer sets the stage for investigating the possible association between dietary factors and mutations in tumor genes known to play a role in the pathogenesis of these neoplasms. With this purpose, we have studied the Ki-ras gene in 108 colorectal cancers using archival… CONTINUE READING

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