Ki-67 immunostaining in uveal melanoma. The effect of pre-enucleation radiotherapy.

@article{Mooy1990Ki67II,
  title={Ki-67 immunostaining in uveal melanoma. The effect of pre-enucleation radiotherapy.},
  author={Cornelia M. Mooy and Paulus T. V. M. de Jong and Theodore H van der Kwast and Paul G. H. Mulder and Martine J. Jager and Dirk J. Ruiter},
  journal={Ophthalmology},
  year={1990},
  volume={97 10},
  pages={1275-80}
}
The reactivity of 33 choroidal and ciliary body melanomas with monoclonal antibody Ki-67, which recognizes a proliferation associated nuclear antigen, has been assessed and compared with clinicopathologic parameters. In 23 cases, 8 Gy irradiation was given 2 days before enucleation. Nonirradiated melanomas had a significantly higher proliferation rate as defined by staining with monoclonal antibody Ki-67 as compared with irradiated tumors (P = 0.007). Similarly, a strong relationship was found… CONTINUE READING

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