Ki-67 as a prognostic marker in adenoid cystic carcinoma assessed with the monoclonal antibody MIB1 in paraffin sections.

@article{Nordgrd1997Ki67AA,
  title={Ki-67 as a prognostic marker in adenoid cystic carcinoma assessed with the monoclonal antibody MIB1 in paraffin sections.},
  author={St{\aa}le Nordg{\aa}rd and Gunnar Franzen and Morten Ebbe Boysen and Tore B Halvorsen},
  journal={The Laryngoscope},
  year={1997},
  volume={107 4},
  pages={531-6}
}
The monoclonal antibody MIB1 recognizing the Ki-67 antigen in formalin-fixed, paraffin-embedded tissue was used to study the proliferative activity in 44 adenoid cystic carcinomas of the salivary glands. The antigen expression was compared with clinical factors, histopathological grading, and prognosis. The Ki-67 value was significantly higher in tumors from patients suffering from treatment failure than in nonfailures (P<0.001). The Ki-67 expression was also higher in tumors exhibiting areas… CONTINUE READING

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